“ Folate Deficiency may increase the risk of depression and reduce the action of antidepressants. Individuals with an inherited polymorphism MTHFR are at high risk for folate deficiency and for MDD"
Stephen M. Stahl MD, PHD
Novel Therapeutics for Depression, CNS Spectrum, 2007
“ Diabetic sensorimotor peripheral neuropathy (DSPN) is prevalent among the population of patients with type 2 diabetes occurring in up to 50% of diabetic patients." -
MacNamara Paper 2016